载脂蛋白E(ApoE)是血浆中主要的载脂蛋白之一,参与机体的脂质代谢及调节胆固醇平衡,其基因多态性与多种疾病相关,在神经系统的正常生长和损伤后的修复过程起重要作用。近来发现其免疫反应性与脑损伤时间有一定规律性,可望将其作为法医检案中判定脑损伤时间的客观指标。 Apolipoprotein E (ApoE), one of the major apolipoproteins in plasma, is involved in the body’s lipid metabolism and cholesterol balance. Its genetic polymorphism is associated with various diseases. After normal growth and damage of the nervous system The repair process plays an important role. Recently found that the immune response and brain damage have a certain regularity of time, is expected to be used as forensic medical examination to determine the objective indicators of brain injury time.