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目的:探讨盆腔孤立性淋巴结转移对宫颈癌患者预后影响,并寻找影响盆腔孤立性淋巴结转移的相关因素。方法:选择宫颈浸润癌患者153例,其中有1枚淋巴结转移者为孤立转移组,无淋巴结转移为无转移组。对比两组患者年龄、临床分期、肿瘤大小、病理类型、分化程度、浸润深度、脉管浸润、宫旁浸润、宫体转移等情况。结果:153例患者中142例接受4～92个月的随访,孤立转移组患者5年生存率为53.1%(17/32),无转移组为83.6%(92/110),差异有统计学意义(P<0.05)。单因素分析中,临床分期、浸润深度、脉管浸润、宫旁浸润为孤立淋巴结转移的相关因素(P<0.05)。Logistic回归分析中显示,临床分期、浸润深度、脉管浸润为影响宫颈癌孤立淋巴结转移的独立危险因素(P<0.05)。结论:宫颈癌患者发生孤立淋巴结转移时预后相对较差,临床分期较晚、宫颈浸润深度≥1/2肌层及有脉管浸润的宫颈癌患者易发孤立淋巴结转移。
Objective: To investigate the influence of pelvic solitary lymph node metastasis on the prognosis of patients with cervical cancer, and to find the factors that influence the pelvic solitary lymph node metastasis. Methods: A total of 153 patients with cervical invasive carcinoma were selected. Among them, one lymph node metastasis was isolated metastasis group and no lymph node metastasis was no metastasis group. Compare the two groups of patients age, clinical stage, tumor size, pathological type, degree of differentiation, depth of invasion, vascular invasion, uterine infiltration, Palace transfer and so on. Results: Of the 153 patients, 142 patients were followed up for 4-92 months. The 5-year survival rate was 53.1% (17/32) in patients with or without metastasis, and 83.6% (92/110) in patients without metastasis. The difference was statistically significant Significance (P <0.05). In univariate analysis, clinical stage, depth of invasion, vascular invasion and uterine infiltration were related factors of isolated lymph node metastasis (P <0.05). Logistic regression analysis showed that clinical stage, depth of invasion and vascular invasion were independent risk factors for cervical lymph node metastasis (P <0.05). Conclusion: The prognosis of cervical cancer patients with isolated lymph node metastasis is relatively poor prognosis, clinical stage, cervical invasion depth of more than 1/2 myometrial and vascular invasion of cervical cancer patients prone to isolated lymph node metastasis.