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慢性阻塞性肺疾病(COPD)是一种以呼吸道气流受限且不完全可逆为主要特征的严重呼吸道疾病,临床上常因反复呼吸道感染、呼吸肌疲劳等出现慢性Ⅱ型呼吸衰竭急性加重,甚至会出现嗜睡、昏迷以致休克而危及患者生命。COPD急性加重期(AECOPD)合并呼吸衰竭的早期,痰液引流问题并不十分突出,而呼吸肌疲劳是主要原因,是应用无创压通气(NPPV)的最佳时机[1]。但在临床使用过程中有一部分患者治疗效果不满意,而被迫采取有创通气方法。
Chronic Obstructive Pulmonary Disease (COPD) is a severe respiratory disease characterized by limited and incompletely reversible airflow in the respiratory tract. Clinically, COPD often causes acute exacerbation of chronic type II respiratory failure due to recurrent respiratory infections and respiratory muscle fatigue. Drowsiness, coma resulting in shock and endanger the lives of patients. In the early stage of acute exacerbation of COPD (AECOPD) combined with respiratory failure, sputum drainage problem is not very prominent, and respiratory muscle fatigue is the main reason, is the best time to use noninvasive pressure ventilation (NPPV) [1]. However, some patients in the clinical use of the treatment effect is not satisfied, and was forced to adopt invasive ventilation method.