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作者选择23名经组织学证实为蕈样肉芽肿(MF)的病人,在PUVA治疗前后每人取4处病理标本,共55处,应用单克隆抗体技术检测T细胞亚群及郎格罕细胞(LC)的分布.计算T辅助细胞(T_H)及T抑制/细胞毒细胞(T_(sc))占淋巴样浸润细胞总数的百分数,并以T_H∶T_(sc)比率来表示结果,表皮LC以每毫米长表皮中所含的数量表示.结果发现真皮内T_H∶T_(sc)比率变化在0.6～18之间,表皮在0.15～10之间.84%病人真皮浸润细胞及55%病人表皮浸润细胞中T_H数量显著多于T_(sc),但9%
The authors selected 23 histologically confirmed patients with mycosis granuloma (MF) to take 4 pathological specimens per patient before and after PUVA treatment. A total of 55 specimens were used to detect T cell subsets and Langerhans cells using monoclonal antibody technology. Distribution of (LC). Calculate the percentage of T-helper cells (T_H) and T-inhibition/cytotoxic cells (T_(sc)) in the total number of lymphoid infiltrating cells, and express the results in terms of T_H:T_(sc) ratio, epidermal LC Expressed in the number of millimeters per millimeter of long epidermis. The results showed that the ratio of T_H:T_(sc) in the dermis was between 0.6 and 18, and the epidermis was between 0.15 and 10. 84% of the patients had dermal infiltrating cells and 55% of the patient’s epidermis. The number of T_H in infiltrating cells was significantly greater than T_(sc), but 9%