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目前,包括二手烟在内的烟草暴露是过早死亡的主要可预防原因。血清可替宁是尼古丁在人体内进行初级代谢后的主要产物,是一种对烟草暴露高度敏感和特异的生物标志物,比自我报告的吸烟状况更为准确。虽然烟草暴露对心血管病危险因素(如动脉粥样硬化)或严重的心血管病结局(如心肌梗死)的有害影响已经确定,但其对亚临床心肌损害(subclinical myocardial injury,SMI)的影响尚不清楚,尤其是在非吸烟
Currently, tobacco exposure, including secondhand smoke, is the main preventable cause of premature death. Serotonin is the major product of nicotine after primary metabolism in the human body. It is a highly sensitive and specific biomarker for tobacco exposure and more accurate than self-reported smoking status. Although the detrimental effects of tobacco exposure on cardiovascular risk factors (such as atherosclerosis) or on severe cardiovascular outcomes (such as myocardial infarction) have been identified, their impact on subclinical myocardial injury (SMI) Not sure yet, especially when it comes to non-smoking