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探讨简易血浆置换 (PE)对免疫性疾病的治疗作用。方法 :分析 2 1例多种免疫性疾病患者PE前后临床情况和 15例患者实验室检验结果。结果 :PE能显著改善多种免疫性疾病患者的临床症状和体征 ,并能显著降低血沉 (45 .2± 2 0 .3vs 17.4± 13.6 )和球蛋白水平 (32 .3± 6 .0vs 2 5 .4± 5 .2 ,均P <0 .0 1) ,另外IgG(15 .2± 5 .1vs 12 .1± 3.5 ) ,IgA(3.1± 1.6vs2 .2± 1.2 )和IgM(1.5± 0 .3vs 1.1± 0 .2 )水平也明显下降 (均P<0 .0 5 )。结论 :PE对多种免疫性疾病有显著的治疗作用
To investigate the therapeutic effect of simple plasma exchange (PE) on immune diseases. Methods: The clinical data of 21 patients with multiple immune diseases before and after PE and the laboratory test results of 15 patients were analyzed. Results: PE could significantly improve the clinical symptoms and signs of patients with multiple immune diseases and significantly reduce the erythrocyte sedimentation rate (45.2 ± 2.03 vs 17.4 ± 13.6) and globulin (32.3 ± 6.0 vs 25 .4 ± 5 .2, all P <0.01), IgG (15.2 ± 5.1 vs 12.1 ± 3.5), IgA (3.1 ± 1.6 vs2.2 ± 1.2) and IgM .3 vs 1.1 ± 0.2) decreased significantly (all P <0.05). Conclusion: PE has a significant therapeutic effect on a variety of immune diseases