听神经病是儿童期耳聋的重要原因之一,新生儿高胆红素血症是导致听神经病的最重要因素,当血清胆红素浓度达到一定水平时可引起新生儿听觉障碍、神经肌肉不协调、智能发育障碍等严重后遗症,甚至可危及生命,因此高胆红素血症已经成为引起小儿听觉损伤的重要病因之一。听神经病的病因、发病机制:目前,对于听神经病的发病原因并不明确,其原因可能是多方面的,大约50%听神经病患者无明确发病原因;约40%与遗传因素有关,例如Char-cot-Marie-Tooth(CMT)综合征,隐性遗传性Friedreich共 Auditory neuropathy is one of the important causes of childhood deafness. Neonatal hyperbilirubinemia is the most important factor leading to auditory neuropathy. When serum bilirubin concentration reaches a certain level, it can cause neonatal hearing impairment and neuromuscular incompatibility , Mental retardation and other serious complications, and even life-threatening, so hyperbilirubinemia has become one of the important causes of hearing loss in children. The etiology and pathogenesis of auditory neuropathy: At present, the cause of auditory neuropathy is not clear, which may be due to many reasons. About 50% of patients with auditory neuropathy have no definite cause. About 40% are related to genetic factors such as Char- cot-Marie-Tooth (CMT) syndrome, recessive hereditary Friedreich co