维生素B_6(VB_6)作为许多转氨酶、脱羧酶的辅酶,在体内经磷酸化,主要以磷酸吡多醛方式发挥作用,参与氨基酸和脂肪代谢,可防治多种疾病。临床上主要用于单纯性VB_6缺乏症,妊娠、放射病以及抗恶性肿瘤药物引起的呕吐,雷米封引起的中枢神经症状和周围神经炎的防治。近年来,VB_6的应用更加广泛,现参考有关文献综述如下。 Vitamin B_6 (VB_6) is a coenzyme of many aminotransferases and decarboxylases. It is phosphorylated in the body and mainly acts on the form of pyridoxal phosphate. It participates in the metabolism of amino acids and lipids and can prevent and treat many diseases. Clinical mainly for simple VB_6 deficiency, pregnancy, radiation sickness and anti-cancer drugs caused by vomiting, Remy seal caused by central nervous symptoms and peripheral neuritis prevention and treatment. In recent years, the application of VB_6 is more extensive, reference to the relevant literature are summarized as follows.