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目的探讨2型糖尿病并发肺结核病(DM-PTB)的危险因素。方法对2001年10月至2002年10月收集的87例新发DM-PTB患者和同期129例单纯2型糖尿病患者进行成组病例对照研究,采用经因子分析改进后的多因素非条件logistic回归模型探索DM-PTB的危险因素。结果不良接触因子、糖尿病病情重、不良习惯因子及食盐摄入量少可增加DM-PTB的发生危险,其比值比(OR)和95%可信区间(95%CI)分别为1.778(1.248~2.534)、1.749(1.221~2.506)、1.614(1.136~2.294)和1.586(1.119~2.248),而良好习惯因子、社会经济地位高、高血压、居住条件好及患糖尿病后饮食控制好可降低DM-PTB的发生危险,其OR值和95%CI分别为0.333(0.218~0.508)、0.508(0.346~0.745)、0.517(0.350~0.764)、0.599(0.413~0.868)和0.630(0.447~0.889)。结论不同性别和年龄的2型糖尿病患者易并发肺结核病的危险因素或保护因素不同,应针对不同人群制定不同的防治策略。
Objective To investigate the risk factors of type 2 diabetes complicated with pulmonary tuberculosis (DM-PTB). Methods A total of 87 patients with newly diagnosed DM-PTB and 129 patients with simple type 2 diabetes mellitus collected from October 2001 to October 2002 were enrolled in a case-control study. The improved multivariate non-conditional logistic regression Model to explore the risk factors of DM-PTB. Results Adverse contact factors, severe diabetes, poor habit factors and low salt intake increased the risk of DM-PTB. The odds ratio (OR) and 95% confidence interval (95% CI) were 1.778 2.534), 1.749 (1.221 ~ 2.506), 1.614 (1.136 ~ 2.294) and 1.586 (1.119 ~ 2.248), while good habit factors, high socioeconomic status, high blood pressure, good living conditions and good diet after diabetes control could reduce DM ORP and 95% CI were 0.333 (0.218-0.508), 0.508 (0.346-0.745), 0.517 (0.350-0.764), 0.599 (0.413-0.868) and 0.630 (0.447-0.889), respectively. Conclusion The risk factors and protective factors of patients with type 2 diabetes mellitus and T2DM with different genders and ages are different from each other. Different strategies should be developed for different populations.