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感染性疾病早期,细菌的粘着性对感染的发展很重要,受到广泛的重视。抗生素的抗菌作用,特别是在亚致死浓度下的抗菌作用同抗菌化疗效果相关。该文对氨基糖苷,β-内酰胶和吡啶酮羧酸衍生物等抗生素对金葡菌(FDA209P菌株对HeLa细胞的粘着性进行探讨。亚致死剂量下(即1/2MIC)西索米星、阿司米星(Astromicin)和链霉素明显增加细菌对HeLa细胞的粘着性(P<0.001),巴龙霉素(Paromomycin)、卡那霉素、庆大霉素和地贝卡星(Dibekacin)也明显增加细菌粘着
Early in infectious diseases, the adhesion of bacteria is very important for the development of the infection, which has received extensive attention. Antibiotic antibacterial effect, especially in the sublethal concentration of antibacterial effect with antibacterial chemotherapy effect. In this paper, the antibacterial activity of aminoglycosides, β-lactones and pyridone carboxylic acid derivatives on Staphylococcus aureus (the adhesion of FDA209P to HeLa cells was studied.) Sulfacets at sub-lethal dose (ie, 1 / 2MIC) , Astromicin and Streptomycin significantly increased bacterial adherence to HeLa cells (P <0.001), Paromomycin, Kanamycin, Gentamicin and Diclofloxacin Dibekacin also significantly increases bacterial adhesion