Isaacs综合征又称持续性肌纤维兴奋综合征(syndrome of continuous muscle fibreactivity)或神经性肌强直(neruomyotonia),是一种罕见的病因尚未明确的综合征。1961年由Isaacs H首次报道,本文总结1984-1998年间我国报道的16例Isaacs综合征患者的临床资料,现报告如下。 Isaacs syndrome, also known as the syndrome of continuous muscle fibreactivity or neruomyotonia, is a rare etiologic syndrome that has not yet been identified. First reported by Isaacs H in 1961, this article summarizes the clinical data of 16 patients with Isaacs syndrome reported in our country from 1984 to 1998, and the report is as follows.