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目的探讨联合应用全身磁共振扩散成像(WB-DWI)技术和CT/MRI在诊断恶性肿瘤全身转移上的临床应用价值。资料与方法选择经临床病理证实的全身恶性肿瘤患者34例,男20例,女14例,年龄22～75岁,平均年龄45岁。所有病例先行CT/MRI检查;而后行WB-DWI检查及后续CT/MRI增强扫描。对照手术、穿刺病理及临床随访结果,统计单独应用CT/MRI影像以及WB-DWI+CT/MRI综合影像对全身转移病灶进行诊断的敏感性、特异性和准确性。统计两者在诊断恶性肿瘤全身转移上的统计学差异。结果CT/MRI常规检查共诊断转移病灶61处,行WB-DWI+CT/MRI诊断转移病灶84处,病理及临床诊断转移病灶83处。CT/MRI常规检查诊断转移病灶符合率约66.37%,WB-DWI+CT/MRI诊断转移病灶符合率约89.11%,两者在诊断恶性肿瘤全身转移上差异具有统计学意义(P<0.05)。结论应用WB-DWI对恶性肿瘤全身转移进行诊断,具有明显的临床应用价值。
Objective To investigate the clinical value of combined application of whole body magnetic resonance diffusion imaging (WB-DWI) and CT / MRI in the diagnosis of systemic metastases of malignant tumors. Materials and Methods 34 cases of systemic malignant tumors confirmed by clinical pathology were selected. There were 20 males and 14 females, aged from 22 to 75 years with a mean age of 45 years. All cases were advanced CT / MRI examination; then WB-DWI examination and follow-up CT / MRI enhanced scan. According to the results of control operation, puncture pathology and clinical follow-up, the sensitivity, specificity and accuracy of CT / MRI and WB-DWI + CT / MRI alone in the diagnosis of systemic metastatic lesions were calculated. Statistical differences between the two in the diagnosis of systemic metastases of malignant tumors. Results Totally 61 metastatic lesions were diagnosed by routine CT / MRI examinations, 84 lesions were identified by WB-DWI + CT / MRI, and 83 lesions were identified by pathology and clinical diagnosis. The coincidence rate of CT / MRI diagnosis of metastatic lesions was 66.37%, and the coincidence rate of WB-DWI + CT / MRI diagnosis of metastatic lesions was 89.11%. There was significant difference between the two in the diagnosis of systemic metastasis of malignant tumors (P <0.05). Conclusion The application of WB-DWI in the diagnosis of systemic metastases of malignant tumors has obvious clinical value.