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用活性炭、硅藻土、氢氧化铝、明矾—活性炭四种不同的吸附剂处理静脉注射用人血免疫球蛋白制剂。结果表明,明矾—活性炭吸附法去除热原质最有效,同时进一步改善了制品外观,提高了制品纯度,蛋白回收率达到75%以上,而且毒性试验和安全试验也符合标准。铝离子残余量偏低
The activated carbon, diatomite, aluminum hydroxide, alum - activated carbon charcoal four different adsorbents for intravenous injection of human immunoglobulin preparations. The results showed that alum - activated carbon adsorption was the most effective method to remove pyrogens, meanwhile, the appearance of products was further improved and the purity of the products was improved. The recovery rate of protein reached more than 75%, and the toxicity and safety tests also met the standards. Low residual aluminum ions