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目的:观察奥曲肽联合普萘洛尔治疗肝硬化上消化道出血的临床疗效。方法:将128例肝硬化上消化道出血患者随机分为对照组和治疗组,每组64例,对照组给予奥曲肽治疗,治疗组给予奥曲肽联合普萘洛尔治疗,根据两组患者治疗后止血情况进行疗效比较。结果:治疗后两组总有效率比较,治疗组总有效率93.8%,对照组总有效率79.7%,两组比较有显著性差异(P<0.05),两组不良反应比较无统计学意义(P>0.05)。结论:奥曲肽联合普萘洛尔治疗肝硬化上消化道出血,疗效显著,具有临床推广的可行性。
Objective: To observe the clinical efficacy of octreotide combined with propranolol in the treatment of upper gastrointestinal bleeding due to cirrhosis. Methods: 128 patients with cirrhosis and upper gastrointestinal bleeding were randomly divided into control group and treatment group, with 64 cases in each group. The control group was treated with octreotide. The treatment group was given octreotide combined with propranolol. According to the two groups of patients after treatment, hemostasis The situation for efficacy comparison. Results: After treatment, the total effective rate was 93.8% in the treatment group and 79.7% in the control group, with significant difference between the two groups (P <0.05). There was no significant difference in adverse reactions between the two groups P> 0.05). Conclusion: The effect of octreotide combined with propranolol in the treatment of upper gastrointestinal bleeding in cirrhosis is significant and has the feasibility of clinical promotion.