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近年来正在研究各种恶性肿瘤患者循环免疫复合物在诊断学和发病学上的意义。各种癌症(如结肠癌、白血病、黑色素瘤等)免疫复合物的出现率为17—94%,关于免疫复合物临床意义的资料也不同。一方面,发现循环免疫复合物水平与淋巴肉芽肿病、急性白血病及某些恶性肿瘤的严重程度有关(Mooney等的研究表明,肿瘤体积缩小则免疫复合物水平降低);另一方面,Румянцев和Rayner的研究表明,如果癌的治疗成功则免疫复合物水平升高。但也有缺乏相关性的报道,为此,本文旨在找出循环免疫复合物在实体癌、白血病和黑色素瘤时与发病阶段的关系,同时试图确定循环免疫复合物出现的频率,并测定复合物中免疫球蛋白和某些抗体的含量。
In recent years, the significance of circulating immune complexes in the diagnosis and pathogenesis of various malignant tumor patients is being studied. The incidence of immune complexes in various types of cancer (such as colon cancer, leukemia, melanoma, etc.) is between 17 and 94%, and the data on the clinical significance of immune complexes are also different. On the one hand, the level of circulating immune complexes is found to be related to the severity of lymphogranulomatous disease, acute leukemia, and certain malignancies (Mooney et al.’s studies show that shrinking the tumor volume reduces immune complex levels); on the other hand, Румянцев and Rayner’s research shows that if the cancer treatment is successful, the level of immune complexes will increase. However, there are also reports of lack of correlation. For this reason, this article aims to find out the relationship between circulating immune complexes and the stage of onset in solid cancers, leukemias, and melanomas. At the same time, it tries to determine the frequency of circulating immune complexes and determine complexes. The content of immunoglobulins and certain antibodies.