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目的:研究视网膜中央静脉阻塞(CRVO)伴黄斑水肿(ME)患者视力与中心凹部光感受器层状态间的相关性。方法:回顾性分析CRVO伴ME患者21例21眼行玻璃体腔内注射曲安奈德(IVTA)之前以及治疗后4周视力及光学相干断层扫描(OCT)影像中视网膜内外光感受器的连接部(IS/OS)的状态。结果:注射IVTA后4周,本组研究中所有患者ME均明显消退。IS/OS(+)组,11眼(52.3%)可以观察到中心凹处部分或完整的IS/OS线。IS/OS(-)组,10眼(47.62%)中心凹处IS/OS线影响缺失。治疗前后两组患者视力及中心凹厚度的改变均具有统计学意义而且治疗前患者的视力情况与IS/OS的状态存在明显的相关性。结论:对于CRVO伴ME患者的治疗,在消除黄斑水肿的同时应该注重对中心凹部光感受器细胞的保护。
Objective: To study the correlation between visual acuity and photoreceptor layer status in central recess in patients with central retinal vein occlusion (CRVO) and macular edema (ME). Methods: 21 cases (21 eyes) of CRVO with ME were retrospectively reviewed. The connections of photoreceptors (IS) before and after intravitreal injection of triamcinolone acetonide (IVTA) and the visual and optical coherence tomography (OCT) / OS) status. Results: Four weeks after IVTA injection, ME in all patients in this study subsided significantly. In the IS / OS (+) group, partial or complete IS / OS lines were observed in 11 of the eyes (52.3%). In the IS / OS (-) group, 10 eyes (47.62%) had no effect on IS / OS lines. Before and after treatment, the changes of visual acuity and foveal thickness in both groups were statistically significant, and there was a significant correlation between visual acuity and IS / OS status before treatment. Conclusion: The treatment of patients with CRVO with ME should eliminate the macular edema and pay attention to the protection of photoreceptor cells in the central recess.