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用于治疗的人单克隆抗体(IllAl,)不仅要有一定的数量,而且要有较高的纯度。体外大规模地培养杂交瘤细胞也许能够保证其数量,但因在培养基中要补充胎牛血清和其它蛋白成分“’,可使后续rll.m-一的纯化相当困难。所以,人们一直在研究人杂交瘤细胞的无血清培养技术,试图
The human monoclonal antibody (IllAl,) used for treatment should not only be in a certain amount, but also have higher purity. Large-scale cultivation of hybridoma cells in vitro may be able to ensure its quantity, but due to the medium to be supplemented with fetal bovine serum and other protein components ’’, can make subsequent rll.m-a purification is very difficult, so people have been Study of human serum-free culture of hybridoma cells, trying to