参芪益气养阴汤治疗小儿反复呼吸道感染随机平行对照研究

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[目的]观察参芪益气养阴汤治疗小儿反复呼吸道感染疗效。[方法]使用随机平行对照方法,将124例住院患者按随机数字表法分为两组。对照组62例转移因子口服液(大连百利天华制药有限公司,国药准字H20054276,10mL/支)10mL/次,2次/d。治疗组62例参芪益气养阴汤(太子参、桔梗、玉竹、瓜蒌各10g,黄芪、金银花、绞股蓝、鱼腥草各12g,灸麻黄4g,泽贝母8g)。烦躁身热,喉部痰鸣加天竺黄、山栀各10g;恶寒流涕,痰青稀加前胡6g,半夏8g;发热、痰黄稠、加连翘、桑叶各8g;痰多咳嗽,痰白色加茯苓4g,法半夏8g,陈皮6g;色红盗汗,干咳无痰加知母4g,玄参5g。1剂/次,水煎200mL,1次/d。连续治疗60d为1疗程。观测临床症状、不良反应。连续治疗1疗程,随访30d,判定疗效。[结果]治疗组治愈18例,显效25例,有效15例,无效4例,总有效率93.55%。对照组治愈8例,显效13例,有效28例,无效13例,总有效率79.03%。治疗组疗效优于对照组(P<0.05)。[结论]参芪益气养阴汤治疗小儿反复呼吸道感染效果显著,值得推广。 [Objective] To observe the therapeutic effect of Shenqi Yiqi Yangyin Decoction on recurrent respiratory tract infections in children. [Methods] Randomized parallel method was used to divide 124 hospitalized patients into two groups according to random number table. The control group of 62 cases of transfer factor oral solution (Dalian Gabriel Tianhua Pharmaceutical Co., Ltd., Zhunzi H20054276, 10mL / support) 10mL / time, 2 times / d. In the treatment group, 62 cases of Shenqi Yiqi Yangyin Decoction (Pseudostellaria heterophylla, Campanulaceae, Polygonatum, Fructus Corni each 10g, Astragalus, honeysuckle, Gynostemma, Houttuynia of the 12g, moxibustion Ephedra 4g, Zeemania 8g). Irritable body heat, throat sputum plus Tianzhu Huang, Gardenia each 10g; nausea runny nose, phlegm sparse rash before 6g, Pinellia 8g; fever, thick yellow sputum, forsythia, mulberry leaves of the 8g; sputum and more Cough, sputum white plus Poria 4g, Pinellia 8g, dried tangerine peel 6g; color red night sweat, dry cough without sputum plus Anemarrhena 4g, Scrophulariaceae 5g. 1 dose / time, decoction 200mL, 1 time / d. Continuous treatment of 60d for a course of treatment. Observed clinical symptoms, adverse reactions. Continuous treatment of a course of treatment, follow-up 30d, to determine the efficacy. [Result] The treatment group cured 18 cases, markedly effective in 25 cases, effective in 15 cases, ineffective in 4 cases, the total effective rate was 93.55%. The control group cured 8 cases, markedly effective in 13 cases, effective in 28 cases, ineffective in 13 cases, the total effective rate was 79.03%. The treatment group was better than the control group (P <0.05). [Conclusion] Shenqi Yiqi Yangyin Decoction treatment of children with recurrent respiratory tract infection effect is significant, it is worth promoting.
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