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妊娠期抑郁症以其逐年增高的发病率、对母婴的严重危害而日益引起人们的关注。雌激素为孕产期一种重要的性激素,已证明与女性抑郁关系密切,其机制可能与影响5羟色胺系统有关。现就妊娠期抑郁症的流行病学现状、诊断、治疗,雌激素与5羟色胺系统作用机制的研究进展作一综述。
Depression in pregnancy with its increasing annual incidence of maternal and child serious harm and increasingly cause for concern. Estrogen, an important sex hormone in the motherhood, has been shown to be closely associated with depression in women, a mechanism that may be related to the effects of the serotonin system. Epidemiological status of depression in pregnancy, diagnosis, treatment, estrogen and serotonin system mechanism of action are reviewed.