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目的分析保山市美沙酮维持治疗(MMT)吸毒人群丙肝病毒(HCV)合并艾滋病病毒(HIV)感染状况,为艾滋合并丙肝患者的人群防控提供依据。方法于2015年7月采用随机抽样调查的方法对保山市MMT吸毒人员进行问卷调查和血清学检测。问卷由中国疾病预防控制中心设计,包括调查对象的人口学基本信息、丙肝知晓率、吸毒方式、接受干预等内容。同时抽取5 ml静脉血进行HIV、HCV抗体检测。使用Epi Data 3.0建立数据库,使用SPSS 19.0软件包进行χ~2检验。结果共调查400人,HCV感染率为55.50%(222/400),HIV感染率为4.00%(16/400),HCV合并HIV感染率为3.25%(13/400)。婚姻状况、职业、首次吸毒年龄不同,HCV感染率不同,差异均有统计学意义(χ~2值分别为6.010、16.179和24.804,P<0.05,P<0.01);注射吸毒人群的HCV感染率、HIV感染率及HCV合并HIV感染率较非注射吸毒人群高,差异均有统计学意义(χ~2值分别为116.087、9.524、7.009,P<0.01);知晓HIV检测结果者HIV感染率和HCV合并HIV感染率低于未知晓者,差异均有统计学意义(χ~2值分别为217.715、176.963,P<0.01)。结论保山市MMT吸毒人群HCV、HIV以及HCV合并HIV感染率比较高,要加强健康教育和行为干预。
Objective To analyze the status of hepatitis C virus (HCV) and HIV infection among drug users in methadone maintenance treatment (MMT) in Baoshan, and to provide basis for prevention and control of HIV / AIDS in people with hepatitis C virus. Methods In July 2015, a random sample survey method was used to conduct questionnaires and serological tests on MMT drug users in Baoshan. Questionnaire designed by the China Center for Disease Control and Prevention, including the demographic basic information surveyed, hepatitis C awareness, drug use, interventions and so on. At the same time extract 5 ml of venous blood for HIV, HCV antibody testing. Database was created using Epi Data 3.0 and chi-square test using SPSS 19.0 software package. Results A total of 400 people were investigated. The HCV infection rate was 55.50% (222/400). The HIV infection rate was 4.00% (16/400). The HCV infection rate was 3.25% (13/400). Marital status, occupation, the age of first drug addiction and different HCV infection rates, the differences were statistically significant (χ ~ 2 values were 6.010,16.179 and 24.804 respectively, P <0.05, P <0.01); HCV infection rate among injecting drug users , HIV infection rate and HCV infection rate were higher than non-injecting drug users, the differences were statistically significant (χ ~ 2 values were 116.087,9.524,7.009, P <0.01); know the HIV test results of HIV infection rate and HCV co-infection rate was lower than those unknown, the differences were statistically significant (χ ~ 2 values were 217.715,176.963, P <0.01). Conclusion The prevalence of HCV, HIV and HCV infection in MMT drug users in Baoshan is relatively high. Health education and behavioral intervention should be strengthened.