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本文用Y-GT酶、G-6-P酶和ATP酶的组织化学反应研究了10例手术切除的肝细胞癌及其周围肝组织的变化。结果表明癌组织与癌周肝组织具有显著酶的差异性。肝癌Y-GT酶的活性,2例显著增强,5例轻度增强,3例无酶的活性。这种变化与癌细胞的分化程度无明显关系,因而本γ-GT酶不能作为肝细胞癌可靠的阳性酶标记。其癌周肝组织γ-GT酶的活性皆有明
In this paper, the histochemical reactions of Y-GTase, G-6-P enzyme and ATPase were used to study the changes of surgical resection of hepatocellular carcinoma and its surrounding liver tissue. The results showed that there was a significant difference in the enzyme between the cancer tissue and the hepatic tissue. The activity of Y-GTase in liver cancer was significantly enhanced in 2 patients, slightly increased in 5 patients, and had no enzymatic activity in 3 patients. This change has no significant relationship with the degree of differentiation of the cancer cells, so this γ-GTase cannot be used as a reliable positive enzyme marker for hepatocellular carcinoma. The activity of γ-GTase in liver tissue around the cancer is clear