在无水及不加催化剂条件下 ,芳香醛和丙二腈于室温研磨进行 Knoevenagel缩合。除 1例收率 6 8%以外 ,其余 11例收率 80 %～ 96 %。与微波辐射法相比 ,在反应及产品分离过程中均无需使用有机溶剂芳香醛和丙二腈的研磨法进行Knoevenagel缩合@刘玲玲 Aromatic aldehydes and malononitrile are ground for Knoevenagel condensation at room temperature with and without catalyst. In addition to a case of a yield of 68%, the remaining 11 cases of 80% to 96% yield. Compared with the microwave radiation method, the reaction and product separation process are not required to use the organic solvent aromatic aldehyde and malononitrile grinding method Knoevenagel condensation @ Lingling Liu