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目的:探讨乙型肝炎肝硬化患者外周血细胞参数的变化及意义。方法:选取健康体检者212例(NC组),慢性乙型肝炎患者152例(CHB组),以及乙型肝炎肝硬化患者224例(LC组),采用XE-2100血细胞分析仪进行外周血常规分析。结果:LC组中性粒细胞和单核细胞的百分比显著高于其他2组,而淋巴细胞显著降低;3组间RBC、Hb和HCT依次降低,而RDW依次增高;3组间PLT和PCT依次降低,LC组MPV、PDW和P-LCR高于NC组但低于CHB组。结论:乙型肝炎肝硬化患者三系血细胞参数均发生改变,且与病程相关。
Objective: To investigate the change and significance of peripheral blood cell parameters in patients with hepatitis B cirrhosis. Methods: 212 healthy subjects (NC group), 152 chronic hepatitis B patients (CHB group) and 224 patients with hepatocirrhosis (LC group) were enrolled in this study. Peripheral blood routine analysis. Results: The percentage of neutrophils and monocytes in LC group was significantly higher than that in the other two groups, but the lymphocytes were significantly decreased. The RBC, Hb and HCT decreased in turn and RDW increased in turn in the three groups. PLT and PCT Decreased, LC group MPV, PDW and P-LCR higher than the NC group but lower than the CHB group. Conclusion: The parameters of three lines of blood cells in patients with hepatitis B cirrhosis are all changed, which are related to the course of disease.