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目的:研究分析甲硫咪唑联合左甲状腺素对甲状腺功能亢进患儿TSH、FT3、FT4水平的影响。方法:选我院2015年9月至2016年9月收治的106例甲状腺功能亢进患儿,依照患儿入院时间先后均分对照组和观察组。对照组采用甲硫咪唑治疗,观察组患儿使用甲硫咪唑联合左甲状腺素展开治疗。对照两组患儿临床治疗效率。结果:治疗前两组患儿TSH、FT3、FT4水平并无差异(P>0.05),治疗后两组患儿TSH、FT3、FT4水平均发现显著改善,且观察组患儿改善效果要显著于对照组(P<0.05);对照组患儿不良反应发生率为20.8%,观察组患儿不良反应发生率为5.7%,两组治疗期间不良反应发生率差异显著(P<0.05)。结论:治疗甲状腺功能亢进患儿期间,采用甲硫咪唑联合左甲状腺素,对改善患儿临床症状具有显著效果,可在临床上推广使用。
Objective: To study the effects of methimazole and levothyroxine on the levels of TSH, FT3 and FT4 in children with hyperthyroidism. Methods: 106 cases of hyperthyroidism admitted to our hospital from September 2015 to September 2016 were divided into control group and observation group according to their admission time. The control group was treated with methimazole, and the observation group was treated with methimazole and levothyroxine. Control two groups of children with clinical treatment efficiency. Results: The levels of TSH, FT3 and FT4 in the two groups before treatment were not significantly different (P> 0.05). After treatment, the levels of TSH, FT3 and FT4 in both groups were significantly improved, and the improvement in the observation group was significant The incidence of adverse reactions in the control group was 20.8%. The incidence of adverse reactions in the observation group was 5.7%. The incidence of adverse reactions in the two groups was significantly different (P <0.05). Conclusion: During the treatment of hyperthyroidism in children during the use of methimazole combined with levothyroxine, to improve the clinical symptoms of children with significant effect, which can be widely used in clinical practice.