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脂肪细胞产生的几种激素可能是联系胰岛素抗性与心血管病两者的一种枢纽机制 ,本研究评估resistin脂肪细胞产生的一种新的激素对内皮激活的影响。方法及结果 内皮细胞 (ECS)与人的重组resistin(10～ 10 0ng/mL ,2 4h)一起孵育 ,评估内皮素 1(ET 1)释放、ET 1mRNA表达、NO生成
Several hormones produced by adipocytes may be a pivotal mechanism linking insulin resistance to cardiovascular disease. This study evaluated the effects of a new hormone produced by resistin on endothelial activation. Methods and Results Endothelial cells (ECS) were incubated with human recombinant resistin (10 ~ 10 0 ng / mL, 24 h) to assess the effects of endothelin 1 (ET 1) release, ET 1 mRNA expression, NO production