论文部分内容阅读
目的观察研究注射热毒宁联合服用利巴韦林注射液治疗儿童手足口病的临床疗效。方法将158例手足口病患儿随机分为两组,治疗组80例,对照组78例。治疗组和对照组均注射利巴韦林注射剂10 mg/(kg.d),用葡萄糖静脉滴注;治疗组同时加入热毒宁0.7 ml/(kg.d)(最大剂量20 ml)注射液。每天1次,5 d为1个疗程,1个疗程后观察比较两组患儿治疗的有效率,记录临床的诊治效果和患儿的症状变化情况如皮疹消退时间、发热及不良反应等,追踪记录1年。结果治疗组患儿的临床总有效率高于对照组(P<0.01);皮疹消退时间、症状减轻时间短于对照组(P<0.05);两组均未发生其他严重并发症(P>0.05)。结论与单一采用利巴韦林注射剂治疗小儿手足口病相比,热毒宁联合利巴韦林注射剂的治疗效果更佳,值得推广应用。
Objective To observe the clinical efficacy of injecting Radixin combined with ribavirin injection in the treatment of hand-foot-mouth disease in children. Methods 158 cases of HFMD were randomly divided into two groups, 80 cases in the treatment group and 78 cases in the control group. The treatment group and the control group were injected ribavirin injection 10 mg / (kg.d), intravenous infusion of glucose; the treatment group while adding heat Tinuvin 0.7 ml / (kg.d) (maximum dose of 20 ml) injection . 1 day, 5 d for a course of treatment, after a course of treatment were observed and compared the effectiveness of treatment of two groups of children, record the clinical diagnosis and treatment of children with symptoms such as rash subsided time, fever and adverse reactions, tracking Record 1 year. Results The total effective rate of the treatment group was higher than that of the control group (P <0.01). The rash subsided time and symptom relief time were shorter than those of the control group (P <0.05). No other serious complications occurred in both groups (P> 0.05 ). Conclusion Compared with the single use of ribavirin injection for the treatment of HFMD in children, Radixin combined with ribavirin injection is more effective and worthy of promotion.