要建立敏感的具有特异性的卵巢癌免疫学诊断方法,首先遇到的问题是卵巢癌是否具有肿瘤特异性抗原或肿瘤相关抗原、抗原的特性及提纯的方法。我室曾在这方面作过一些研究。本实验应用亲和层析法纯化抗原,并用免疫耐受法制备的特异性较高的抗血清,进一步研究了卵巢囊腺癌组织抗原的特性,并对该等抗原的分子量作了检测。 To establish a sensitive and specific method of immunological diagnosis of ovarian cancer, the first problem encountered is whether ovarian cancer has tumor-specific antigen or tumor-associated antigen, antigen characteristics and purification methods. My room had some research in this area. In this study, the antigen was purified by affinity chromatography, and the specific antiserum raised by immune tolerance method was used to further study the antigenic characteristics of ovarian cystadenocarcinoma tissue and the molecular weight of these antigens was detected.