目的了解小儿伤寒并溶血性尿毒症综合征(HUS)的临床特点、诊断要点,探讨其治疗方法及效果。方法对10例伤寒并溶血性尿毒症综合征患儿的临床表现、实验室检查、综合治疗措施及转归资料,进行综合分析。结果本组病例均为学龄前或学龄儿童,HUS 症状典型,伤寒症状以持续高热、消化道症状突出,明确诊断、综合治疗10 d 内血红蛋白上升,尿量正常,20d 内所有症状逐渐恢复。结论对小儿伤寒并溶血性尿毒症综合征采取综合治疗预后较好,与预后有关的因素是少尿期持续时间。激素治疗可阻止病情进展。 Objective To understand the clinical features, diagnosis and treatment of typhoid fever and hemolytic uremic syndrome (HUS) in children and discuss its treatment methods and effects. Methods A total of 10 cases of typhoid fever and hemolytic uremic syndrome in children with clinical manifestations, laboratory tests, comprehensive treatment measures and outcome data, a comprehensive analysis. Results All cases were preschool or school-age children. The symptoms of HUS were typical, typhoid fever continued to be hot, gastrointestinal symptoms were prominent, and the diagnosis was diagnosed. The hemoglobin increased within 10 days after treatment and the urine output was normal. All the symptoms recovered within 20 days. Conclusion The comprehensive treatment of typhoid fever and hemolytic uremic syndrome in children with good prognosis, prognosis-related factors is the duration of oliguria. Hormone therapy can prevent the progression of the disease.