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目的探讨早期微量喂养与非营养性吸吮联合治疗窒息后新生儿喂养不耐受的临床疗效。方法选取新余市妇幼保健院2013年5月—2014年6月收治的窒息后新生儿喂养不耐受患儿86例,按照随机数字表法分为观察组和对照组,各43例。对照组患儿给予非营养性吸吮治疗,观察组患儿在上述基础上给予早期微量喂养联合非营养性吸吮治疗。比较两组患儿恢复出生体质量时间、全量肠内营养时间以及治疗后血清指标,统计两组患儿并发症发生率。结果观察组患儿恢复出生体质量时间以及全量肠内营养时间短于对照组,总胆红素水平低于对照组,清蛋白以及前清蛋白水平高于对照组,并发症发生率低于对照组,差异有统计学意义(P<0.05)。结论早期微量喂养联合非营养性吸吮联合治疗窒息后新生儿喂养不耐受的临床疗效显著,能够帮助患儿快速恢复出生体质量且达到全量肠内营养,同时并发症发生率较低。
Objective To explore the clinical efficacy of early micronutrient feeding combined with non-nutritive sucking on neonatal feeding intolerance after asphyxia. Methods Totally 86 neonates with intolerance were enrolled in the MCH hospital of Xinyu City from May 2013 to June 2014 and were divided into observation group and control group with 43 cases in each group according to random number table. The control group of children given non-nutritive sucking treatment, the observation group of children on the basis of the above given early micronutrient combined with non-nutritive sucking treatment. The recovery time of birth weight, total enteral nutrition time and serum indexes after treatment were compared between the two groups. The incidence of complications in both groups were statistically analyzed. Results The recovery time of birth weight and the total enteral nutrition time in the observation group were shorter than those in the control group, the total bilirubin level was lower than that in the control group, and the levels of albumin and prealbumin were higher than those in the control group. The complication rate was lower in the observation group Group, the difference was statistically significant (P <0.05). Conclusion Early micronutrient combined with non-nutritive sucking combined treatment of apnea neonates with intolerance clinical efficacy was significant, can help children with rapid recovery of birth weight and achieve full enteral nutrition, while the incidence of complications is low.