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目的探讨青少年肥胖家族史与高三酰甘油血症‐腰围表型(HTWC)的关系。方法采用分层整群随机抽样方法,对秦皇岛地区3136名13~17岁汉族青少年进行横断面调查。根据父母有无肥胖分为无肥胖家族史组( n=1967)和有肥胖家族史组( n=1169)。检测调查对象的三酰甘油(T G )水平及测量身高、体质量及腰围(WC),并计算体质量指数(BMI)。以WC≥同年龄同性别青少年WC的90百分位值且 TG≥1.47 mmol/L定义为HTWC表型。结果有肥胖家族史青少年平均WC和TG均显著高于无肥胖家族史青少年( P <0.05)。有肥胖家族史青少年 HTWC表型高于无肥胖家族史青少年(4.4% vs 2.5%,χ2=8.468, P =0.004)。以 HTWC表型为因变量,以年龄、性别和肥胖家族史为自变量,行多因素logistic回归显示,肥胖家族史(OR=1.735,95% CI:1.167~2.578,P=0.006)为HTWC表型的独立危险因素。结论肥胖家族史与青少年 HTWC表型密切相关,为青少年 HTWC表型的独立危险因素。“,”[Objective]To explore the relationship between a family history of obesity and hypertriglyceridemic‐waist (HTWC) phenotype in adolescents .[Methods]A cross‐sectional study was conducted for 3 ,136 Han adoles‐cents aged 13~17 years in Qinhuangdao through stratified and cluster sampling .The HTWC phenotype was defined as serum triglyceride concentrations ≥1 .47 mmol/L and waist circumference ≥90th percentile for age and gender . Based on a family history of obesity ,they were divided into two groups of positive family history ( n =1169) and negative family history ( n =1967) .The triglyceride concentrations ,height ,weight and waist circumference were measured .And body mass index was calculated .[Results]Waist circumference and serum triglyceride were significant‐ly higher in adolescents with a family history of obesity than those in adolescents without a family history of obesity ( P<0 .05) .The prevalence of HTWC phenotype was significantly higher in adolescents with family history than that in those without family history (4 .4% vs 2 .5% ,χ2 =8 .468 ,P =0 .004) .After adjusting for gender and age ,the prevalence of HTWC phenotype among adolescents with family history was 1 .735 (95% CI:1 .167~2 .578 ,P =0 .006) folds of those without family history .[Conclusion]A significant correlation exists between a family history of obesity and HTWC phenotype .And it suggests that a family history of obesity is an independent risk factor for HT‐WC phenotype .