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目的探讨、分析重症支原体肺炎(RMPP)的临床资料,为临床早期诊断、治疗提供依据。方法回顾性分析2015年3月~2016年3月100例重症支原体肺炎患儿(观察组)和101例轻症支原体肺炎患儿(对照组)的住院病历资料,汇总年龄、超敏CRP、血沉、心肌酶谱、T淋巴细胞亚群、病程1周及出院前1d的肺炎支原体抗体的临床数据进行分析。结果观察组超敏CRP、血沉、LDH、CD_8~+水平明显高于对照组,观察组CD_3~+,CD_4~+及CD_4~+/CD_8~+水平明显低于对照组,差异有统计学意义(P<0.01)。结论重症支原体肺炎早期检测肺炎支原体抗体假阴性明显,不易于发现。因此,通过对超敏CRP、血沉、心肌酶谱及T淋巴细胞亚群的密切关注对于重症支原体肺炎的预防、诊断、治疗有着重要意义。
Objective To investigate and analyze the clinical data of severe mycoplasma pneumonia (RMPP) and provide the basis for early clinical diagnosis and treatment. Methods The hospital records of 100 children with severe mycoplasma pneumonia (the observation group) and 101 children with mild mycoplasma pneumonia (the control group) from March 2015 to March 2016 were retrospectively analyzed. The age, hypersensitivity CRP, erythrocyte sedimentation rate , Myocardial enzymes, T lymphocyte subsets, clinical course of 1 week and 1d before discharge of Mycoplasma pneumoniae clinical data were analyzed. Results The levels of hypersensitive CRP, erythrocyte sedimentation rate, LDH and CD_8 ~ + in the observation group were significantly higher than those in the control group. The levels of CD_3 ~ +, CD_4 ~ + and CD_4 ~ + / CD_8 ~ + in the observation group were significantly lower than those in the control group (P <0.01). Conclusions The detection of mycoplasma pneumoniae antibody in the early stage of severe mycoplasma pneumonia is obviously false-negative, which is not easy to find. Therefore, through the close attention of hypersensitivity CRP, ESR, myocardial enzymes and T lymphocyte subsets for the prevention, diagnosis, treatment of severe mycoplasma pneumonia is of great significance.