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目的:探讨脑梗死采取奥扎格雷联合丹参治疗的临床疗效。方法:选取100例茂名市茂南区新坡卫生院2013年5月至2015年5月接收的脑梗死患者,随机分为对照组与观察组,每组各50例,对照组给予常规治疗,观察组给予常规治疗+奥扎格雷联合丹参治疗,观察两组治疗疗效。结果:治疗后,观察组患者临床总有效率相比于对照组显著要高,组间比较,差异具有统计学意义(P<0.05);两组日常生活能力量表(ADL)、卒中量表(NIHSS)评分均有所改善,而观察组改善程度更显著,组间比较,差异具有统计学意义(P<0.05);两组血液流变学中高切、低切及血浆黏度,观察组较对照组显著要优,组间比较,差异具有统计学意义(P<0.05),且观察组纤维蛋白原显著低于对照组,组间比较,差异具有统计学意义(P<0.05)。结论:脑梗死采取奥扎格雷联合丹参治疗,可改善神经功能缺损,改善血液流变性,提高日常生活能力,疗效显著且安全性好。
Objective: To investigate the clinical efficacy of Ozagrel combined with Salvia miltiorrhiza in cerebral infarction. Methods: 100 cases of cerebral infarction received by Xinpo Hospital, Maonan District, Maoming from May 2013 to May 2015 were randomly divided into control group and observation group, with 50 cases in each group. The control group was given routine treatment, The observation group was given conventional treatment plus ozagrel combined with Salvia miltiorrhiza. The curative effect of the two groups was observed. Results: After treatment, the total effective rate of the observation group was significantly higher than that of the control group. There was significant difference between the two groups (P <0.05). The ADL, Stroke Scale (NIHSS) score improved, while the observation group improved more significantly, between groups, the difference was statistically significant (P <0.05); two groups of high-cut, low cut and plasma viscosity, (P <0.05). The fibrinogen in the observation group was significantly lower than that in the control group. The differences between the two groups were statistically significant (P <0.05). Conclusion: Ozagrel combined with Salvia miltiorrhiza in cerebral infarction can improve neurological deficit, improve hemorrheology and improve daily living ability, with significant curative effect and good safety.