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雌激素在生长、分化及雌性生殖功能中扮演重要角色。雌激素的作用是由靶细胞内雌激素受体 (ｅｓｔｒｏｇｅｎｒｅｃｅｐｔｏｒ,ＥＲ)所介导的 ,ＥＲ是类固醇受体超家族成员之一 ,它是通过与雌激素受体反应元件结合调控基因转录 ,而在靶细胞中发挥功能的。ＥＲ有ＥＲα、ＥＲβ?
Estrogen plays an important role in growth, differentiation and female reproductive function. The role of estrogen is mediated by estrogen receptors (ERs) in target cells. ER is a member of the steroid receptor superfamily that regulates gene transcription by binding to estrogen receptor response elements Functioning in target cells. ER ERα, ERβ?