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目的 :探讨小剂量阿斯匹林预防妊娠高血压综合征 (妊高征 )的作用机理 ,观察临床疗效。方法 :对孕 2 8W左右预测妊高征阳性者 10 0例随机分两组。对照组常规处理 ;阿斯匹林组在常规处理的基础上加用小剂量阿斯匹林 6 0mg d口服 ,直至临产。结果 :小剂量阿斯匹林组的临产前妊高征阳性率 ,轻中度妊高征 ,重度妊高征 ,临产前外周血流阻力 (TPR)至临产前 ,平均动脉压均明显低于对照组 ,产时出血量无明显差异。结论 :小剂量阿斯匹林预防妊高征有重要的临床价值。
Objective: To investigate the mechanism of low dose aspirin in preventing pregnancy induced hypertension (PIH) and to observe the clinical effect. Methods: Pregnancy 28 W or so predict pregnancy-induced hypertension positive 10 cases were randomly divided into two groups. Control group routine treatment; aspirin group on the basis of conventional treatment plus a small dose of aspirin 60mg d oral until labor. Results: The positive rates of pre-natal pregnancy-induced syndrome (PIH), mild to moderate pregnancy-induced hypertension (PIH), severe PIH, prenatal peripheral blood flow resistance (TPR), and mean arterial pressure were significantly lower in low-dose aspirin group Control group, there was no significant difference in the amount of bleeding during labor. Conclusion: Low-dose aspirin has important clinical value in preventing PIH.