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目的 :了解贺州地区重型肝炎中甲～庚型肝炎病毒感染状况及其与发病的关系。方法 :应用酶联免疫吸附法检测血清中的抗 HAV- Ig M、HBs Ag、HBe Ag、抗 HBC、抗 HCV- Ig M、抗 HDV- Ig M、抗 HEV- Ig M、抗 HEV- Ig G、抗 HGV- Ig M。结果 :重肝组病毒检出率有 HAV6 .79%、HBV77.6 8%、HCV6 .79%、HDV5 .36 %、HEV32 .14%、HGV8.0 3% ,其中 HBV、HCV、HGV显著高于对照组 ;36 .5 1%重肝病例是病毒重叠感染 ,共有 13种病毒感染模式 ;近半数病毒重叠感染是 HBV+ HEV,其病死率高达 70 %。结论 :贺州地区重肝甲～庚型病毒均有不同程度感染 ,HBV、HEV是主要危险因素 ,两者重叠感染机率高 ,预后差 ;HGV在重肝发病作用值得重视。
Objective: To understand the status of Hepatitis A ~ Hepatitis G virus infection in Hepatitis in Hezhou and its relationship with the pathogenesis. Methods: Serum anti-HAV-Ig M, HBs Ag, HBe Ag, anti-HBC, anti-HCV-Ig M, anti-HDV-Ig M, anti-HEV-Ig M, anti-HEV-Ig G were detected by enzyme-linked immunosorbent assay , Anti-HGV-Ig M. Results: The detection rate of severe hepatitis was HAV6.79%, HBV77.68%, HCV6.79%, HDV5.36%, HEV32.14%, HGV8.0 3%, among which HBV, HCV and HGV were significantly higher In the control group, 36.5% of the cases of severe hepatitis were viral infection and there were 13 patterns of virus infection. Nearly half of the viruses were HBV + HEV, with a mortality rate of 70%. CONCLUSION: Hepatitis A and G are all infected to varying degrees in Hezhou area. HBV and HEV are the main risk factors. Their overlapping infection rate is high and the prognosis is poor. The role of HGV in severe liver disease deserves attention.