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目的:探讨乳腺原发性血管肉瘤的临床病理特点和鉴别诊断。方法:对2例乳腺原发性血管肉瘤进行组织形态学和免疫组化分析。并复习文献。结果:乳腺原发性血管肉瘤几乎均发生于女性。临床表现不典型,组织学变化大,肿瘤通常表达CD31和CD34,目前主要采用手术治疗。结论:乳腺原发性血管肉瘤较少见。预后与肿瘸分化程度有关。
Objective: To investigate the clinicopathological characteristics and differential diagnosis of primary angiosarcoma in breast. Methods: Two cases of primary angiosarcoma of the breast were histomorphologically and immunohistochemically analyzed. And review the literature. Results: Primary breast angiosarcomas occurred in almost all women. Clinical manifestations of atypia, histological changes, tumors usually express CD31 and CD34, the current main surgical treatment. Conclusion: The primary angiosarcoma of the breast is rare. Prognosis and lameness related to the degree of differentiation.