论文部分内容阅读
目的了解美沙酮维持治疗的出勤率与海洛因成瘾者性行为和梅毒发病的关系,为控制海洛因成瘾者梅毒发病提供依据。方法对美沙酮门诊中梅毒血清学检测为阴性,保持美沙酮维持治疗1年的121名海洛因成瘾者,再次进行梅毒血清检测,按服药期间出勤率高低分组比较性伴数、安全套使用情况和梅毒发病率。结果梅毒总发病率为5.79%,7例新发梅毒感染者均为治疗期间性伴数>1人且安全套使用率<50%者,服药出勤率高组安全套使用率高于服药出勤率低组(χ2=4.25,P=0.039),但性伴数和梅毒发病率两组间差异无统计学意义(均有P>0.05)。结论性传播途径是梅毒感染的主要途径,服药出勤率高的海洛因成瘾者安全套使用情况好。因此,在美沙酮门诊中应重视加强海洛因成瘾者性传播途径的综合干预措施。
Objective To understand the relationship between the attendance of methadone maintenance therapy and the incidence of syphilis in heroin addicts and to provide basis for controlling the incidence of syphilis in heroin addicts. Methods A total of 121 heroin addicts who had been tested for methadone in the outpatient setting for methadone for one year were included in the study. Methadyremia was detected again in the methadone clinics. The number of sex partners in the attendance group, the condom use and the incidence of syphilis rate. Results The overall incidence of syphilis was 5.79%. Seven cases of new syphilis were all with sexual partners> 1 and the condom use rate was less than 50%. The condom use rate was higher in taking medication than in medication taking group (χ2 = 4.25, P = 0.039), but there was no significant difference in the incidence of syphilis and syphilis among the two groups (P> 0.05). Conclusions Sexual transmission is the main way of syphilis infection, condom usage is good for heroin addicts with high attendance rate. Therefore, comprehensive interventions to enhance sexual transmission of heroin addicts should be emphasized in methadone clinics.