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目的观察米非司酮治疗功能失调性子宫出血患者的临床效果。方法将医院收治的功能失调性子宫出血患者90例随机分为观察组和对照组,每组45例。对照组予以性激素避孕药1号联合甲基睾丸素治疗,观察组予以米非司酮治疗。观察2组临床效果、不良反应发生情况及复发率。结果完成相应治疗后,观察组有效率为93.33%,明显高于对照组的73.33%(P<0.05);观察组不良反应发生率为2.22%,明显低于对照组的22.22%(P<0.01);观察组复发率为4.44%,低于对照组的17.78%(P<0.05)。结论针对育龄期及绝经过渡期功能失调性子宫出血患者予以米非司酮治疗临床效果显著,具有较高的安全性,对于促进患者预后具有积极意义。
Objective To observe the clinical effect of mifepristone in patients with dysfunctional uterine bleeding. Methods Totally 90 patients with dysfunctional uterine bleeding admitted to the hospital were randomly divided into observation group and control group, with 45 cases in each group. The control group was treated with sex hormonal contraceptive 1 and methyltestosterone, and the observation group was treated with mifepristone. The clinical effects, the incidence of adverse reactions and the recurrence rate in the two groups were observed. Results After the corresponding treatment, the effective rate of the observation group was 93.33%, which was significantly higher than that of the control group (73.33%, P <0.05). The incidence of adverse reactions in the observation group was 2.22%, significantly lower than that of the control group (22.22%, P <0.01) ). The recurrence rate in the observation group was 4.44%, which was lower than that in the control group (17.78%, P <0.05). Conclusion The clinical efficacy of mifepristone in patients with childhood and menopausal transitional dysfunctional uterine bleeding is significant, with high safety, which is of positive significance to promote the prognosis of patients.