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目的：观察新疆阿尔泰人工虫草菌丝体（ＣＣＭ）及培养液（ＣＣＬ）的护肝作用。方法：采用Ｄ－氨基半乳糖（Ｄ－Ｇａｌ）致大鼠小鼠实验性肝损伤。结果：ＣＣＭ及ＣＣＬ灌胃可使小鼠肝损伤升高的血清谷丙转氨酶及谷草转氨酶明显下降（Ｐ＜０．０５），而对大鼠肝损伤升高的谷丙转氨酶及谷草转氨酶作用不明显（Ｐ＞０．０５），但可使大鼠肝损伤升高的血清前白蛋白明显下降（Ｐ＜０．０５）。病理组织切片显示，ＣＣＭ和ＣＣＬ对大鼠及小鼠肝损伤的肝组织均有一定的保护作用。结论：ＣＣＭ和ＣＣＬ有一定的护肝作用
Objective: To observe the hepatoprotective effects of Cordyceps mycelia (CCM) and culture fluid (CCL) in Xinjiang Altai. METHODS: Experimental liver injury was induced in rats with D-galactosamine (D-Gal). RESULTS: Gastric CCM and CCL administration significantly decreased serum alanine aminotransferase and aspartate aminotransferase in mice with elevated hepatic injury (P<0.05). However, the effects of elevated alanine aminotransferase and aspartate aminotransferase on rat liver injury were not affected. Significantly (P>0.05), serum pre-albumin that increased liver injury in rats was significantly decreased (P<0.05). Histopathological sections showed that CCM and CCL had protective effects on hepatic tissue damage in rats and mice. Conclusion: CCM and CCL have a certain protective effect on liver