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DNA聚合酶 β( polymeraseβ ,Polβ)是人体内主要的碱基切除修复聚合酶 ,该酶在其结构进化过程中相当保守 ,说明它在生命活动功能中起着重要作用。自从重组全DNA技术克隆出了DNA聚合酶 β的cDNA以后 ,它的生物学功能越来越受到人们的关注 ,被称为生物进化过程的“看家酶”。DN
Polymβis the major base excision repair polymerase in human body. The enzyme is quite conservative in its structural evolution, indicating that it plays an important role in the life function. Since the cloning of DNA polymerase β cDNA by recombinant DNA technology, its biological function has drawn more and more attention. It is called “housekeeping enzyme” in biological evolution. DN