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目的 评价弥可保与盐酸丁咯地尔联合治疗糖尿病周围神经病变的效果。方法 将糖尿病周围神经病变患者随机分为 2组。治疗组 :2 2例 ,盐酸丁咯地尔 30mg溶于生理盐水 2 5 0ml静脉滴注 ,1次 /d ,同时每日肌注弥可保 5 0 0 μg ,共 6周 ;对照组 :2 0例 ,单用弥可保肌注 ,每日 5 0 0 μg ,共 6周。结果 治疗组有效率明显高于对照组 (6 8%与 4 5 % ,P <0 .0 5 ) ,神经传导功能有明显提高 (P <0 .0 5 )。结论 弥可保与盐酸丁咯地尔联合应用可明显提高糖尿病周围神经病变的治疗效果。
Objective To evaluate the efficacy of methycobal and buflomedil hydrochloride in the treatment of diabetic peripheral neuropathy. Methods Diabetic peripheral neuropathy patients were randomly divided into two groups. Treatment group: 22 cases, Buflomedil hydrochloride 30mg dissolved in 250ml normal saline intravenous infusion, 1 times / d, while daily intramuscular mecoprop 500 hours for 6 weeks; control group: 2 0 cases, alone Mi Kebao muscle injection, daily 500 g, a total of 6 weeks. Results The effective rate of the treatment group was significantly higher than that of the control group (68% vs 45%, P <0.05), and the nerve conduction function was significantly improved (P <0.05). Conclusion Combination of miconazole and buflomedil hydrochloride can significantly improve the therapeutic effect of diabetic peripheral neuropathy.