1960年后,急性淋巴细胞白血病(ALL)治疗的成功率逐年稳定提高。ALL的5年无病生存率在儿童高达80％,在成人也接近40％(表1)。如果将复发但经治疗缓解效果良好的病人包括在内,应用目前治疗方法的治愈率(定义为至少10年的无病生存)在儿童能达80％,在成人达40％。进一步应用造血干细胞移植能提高ALL某些亚型的预后,但不是全部,这就提 After 1960, the success rate of treatment of acute lymphoblastic leukemia (ALL) increased steadily year by year. Five-year disease-free survival for ALL is as high as 80% in children and close to 40% in adults (Table 1). Cure rates (defined as disease-free survival of at least 10 years) using current treatments should be 80% in children and 40% in adults, if you include patients who have relapsed but are well treated for remission. Further application of hematopoietic stem cell transplantation can improve the prognosis of some subtypes of ALL, but not all of them