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目的:分析丹参多酚酸盐联合左卡尼汀治疗稳定型心绞痛患者的临床疗效。方法:126例稳定型心绞痛患者按照数字表法随机分成两组。对照组63例仅给予左卡尼汀治疗,观察组63例在左卡尼汀治疗基础上联合应用丹参多酚酸盐。比较两组肌钙蛋白、超敏C反应蛋白、心电图改善情况、不良反应以及心功能各项指标。结果:观察组c Tn I(0.56±0.33)μg/L、hs-CRP(2.79±0.66)mg/L、LVEF(51.23±4.92)%、E/A(1.16±0.43)、心电图改善总有效率(98.41%)明显优于对照组c Tn I(0.72±0.28)μg/L、hs-CRP(3.05±0.43)mg/L、LVEF(49.18±4.34)%、E/A(0.95±0.24)、心电图改善总有效率(85.71%),差异有统计学意义(P<0.05)。两组用药不良反应无显著差别(P>0.05)。结论:稳定型心绞痛患者采用丹参多酚酸盐及左卡尼汀联合治疗,能够扩张血管,改善心功能,减少心绞痛发作次数,有助于控制病情发展,满足患者期望值。
Objective: To analyze the clinical effect of Salviae miltiorrhizae polyphenols combined with levocarnitine in patients with stable angina pectoris. Methods: 126 patients with stable angina were randomly divided into two groups according to the digital meter method. Sixty-three patients in the control group were treated with levocarnitine only, and 63 patients in the observation group were treated with levocarnitine on the basis of salvianolate. Compare the two groups of troponin, high-sensitivity C-reactive protein, ECG improvement, adverse reactions and cardiac function indicators. Results: The total effective rate of ECG in the observation group was 0.56 ± 0.33 μg / L, 2.39 ± 0.66 mg / L, LVEF was 51.23 ± 4.92% and E / A was 1.16 ± 0.43 (98.41%) was significantly higher than that of control group (0.72 ± 0.28) μg / L and 3.05 ± 0.43 mg / L, LVEF 49.18 ± 4.34% and E / A 0.95 ± 0.24 The total effective rate of ECG improvement (85.71%), the difference was statistically significant (P <0.05). Adverse reactions between the two groups showed no significant difference (P> 0.05). Conclusion: Salviae miltiorrhizae polyphenols and levocarnitine combined therapy can stabilize angina pectoris, dilate blood vessels, improve cardiac function, reduce the number of angina pectoris, help to control the progression of the disease and meet the expectations of patients.