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目的观察比较2种不同抗甲状腺药物治疗甲状腺功能亢进症(甲亢)的疗效。方法选取医院收治的甲亢患者40例,分为对照组19例和观察组21例。对照组给予丙硫氧嘧啶口服,观察组给予甲硫咪唑口服,观察2组患者治疗后的效果及不良反应发生情况。结果观察组总有效率为95.24%,高于对照组的78.95%(P<0.05);观察组不良反应发生率为9.52%,低于对照组的31.58%(P<0.05)。结论甲硫咪唑可有效控制患者的病情,对肝功能的损伤较小,且不良反应发生率较低,值得临床广泛应用。
Objective To observe and compare the efficacy of two different antithyroid drugs in the treatment of hyperthyroidism (hyperthyroidism). Methods 40 cases of hyperthyroidism admitted to hospital were divided into control group (n = 19) and observation group (n = 21). In the control group, propylthiouracil was administered orally, and the observation group was given methimazole orally. The effects and the adverse reactions of the two groups after treatment were observed. Results The total effective rate in the observation group was 95.24%, which was higher than that in the control group (78.95%, P <0.05). The adverse reaction rate in the observation group was 9.52%, which was lower than that in the control group (31.58%, P <0.05). Conclusion Methimazole can effectively control the patient’s condition, less damage to liver function, and the incidence of adverse reactions is low, it is widely used in clinical.