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目的观察通心络胶囊联合氯吡格雷治疗冠心病心绞痛的临床疗效。方法选取冠心病心绞痛患者220例,采用随机数字表法将其分为治疗组和参考组各110例。2组冠心病心绞痛患者均采用常规治疗,在此基础上,参考组采用氯吡格雷治疗,治疗组采用通心络胶囊联合氯吡格雷治疗。治疗后比较2组患者的临床疗效,观察2组患者的心绞痛持续时间,硝酸甘油用量及心绞痛发作次数。结果治疗组总有效率为91.82%高于参考组的73.64%(P<0.05);治疗后2组患者的心绞痛持续时间短于治疗前,硝酸甘油用量及心绞痛发作次数均少于治疗前,且治疗组变化幅度大于参考组,差异均有统计学意义(P<0.05)。结论采用通心络胶囊联合氯吡格雷治疗冠心病心绞痛患者,可显著提高临床疗效,减少硝酸甘油用量,改善患者的临床症状,具有临床推广应用价值。
Objective To observe the clinical effect of Tongxinluo capsule combined with clopidogrel in the treatment of coronary heart disease angina pectoris. Methods 220 cases of coronary heart disease angina pectoris were selected, which were divided into treatment group and reference group of 110 cases by random number table method. Two groups of patients with coronary heart disease angina were treated with conventional therapy, on this basis, the reference group with clopidogrel treatment, the treatment group Tongxinluo capsule combined with clopidogrel treatment. After treatment, the clinical efficacy of two groups were compared. The duration of angina pectoris, the dosage of nitroglycerin and the number of angina pectoris were observed in two groups. Results The total effective rate in the treatment group was 91.82%, which was significantly higher than that in the reference group (73.64%, P <0.05). The duration of angina pectoris in the two groups was shorter than that before treatment, the dosage of nitroglycerin and the number of angina pectoris were less than before treatment The treatment group changed more than the reference group, the differences were statistically significant (P <0.05). Conclusion Tongxinluo capsule combined with clopidogrel in patients with coronary heart disease angina pectoris can significantly improve clinical efficacy, reduce the amount of nitroglycerin and improve the clinical symptoms of patients with clinical application value.