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为了解前列腺素E1(PGE1)治疗急性胰腺炎(AP)的疗效,将54例AP随机分为治疗组26例,对照组28例。两组除禁食、输液抗生素等相同外,治疗组用PGE1 200μg加5%葡萄糖液500ml静滴,每天1次,连用3天。同时观察腹痛及血、尿淀粉酶变化。结果表明:治疗组腹痛消失及血尿淀粉酶恢复至正常时间均较对照组明显缩短(P<0.01)。提示PGE1可提高AP疗效。
To understand the efficacy of prostaglandin E1 (PGE1) in the treatment of acute pancreatitis (AP), 54 AP patients were randomly divided into treatment group (n = 26) and control group (n = 28). In addition to the two groups of fasting, infusion of antibiotics and the same, the treatment group with PGE1 200μg plus 5% glucose solution 500ml intravenous infusion, once daily for 3 days. At the same time observe abdominal pain and blood, urine amylase changes. The results showed that the disappearance of abdominal pain and the return of hematuria to amylase in the treatment group were significantly shorter than those in the control group (P <0.01). Tip PGE1 can improve AP efficacy.