原发性醛固酮增多症形成的高血压,常可经肾上腺切除而得到治愈。但是,Conn报告36.5％的原发性醛固酮增多症病人术后仍有高血压。Biglieri等也证明40%的病例在肾上腺切除后高血压仍持续存在。与之有关的几个因素包括压力感受器的重建,血液动力学改变、血管结构改变、血管对加压物质敏感性的变化及肾脏功能或结构的改变等。本文主要目的是阐明原发性醛固酮增多症在行肾上腺切除后血压和肾脏功能及结构改变间的关系。 Hypertension caused by primary aldosteronism can often be cured by adrenalectomy. However, Conn reports that 36.5% of patients with essential aldosteronism still have hypertension postoperatively. Biglieri et al. Also demonstrated that hypertension persisted in 40% of cases after adrenalectomy. Several related factors include baroreceptor rebuilding, hemodynamic changes, changes in vascular structure, changes in vascular sensitivity to pressurized substances and changes in renal function or structure. The main purpose of this paper is to elucidate the relationship between blood pressure and renal function and structural changes in patients with primary aldosteronism after adrenalectomy.