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颅底肿瘤侵犯斜坡、岩骨及邻近区,成功切除肿瘤而不损伤重要神经很困难。最近5年中,对经治103例颅底肿瘤患者,其中20例经幕上联合进路切除肿瘤进行回顾(9例神经鞘瘤、6例脑膜瘤、2例表皮样瘤、1例广泛性基底细胞癌、1例脑桥海绵状畸形及1例基底动脉瘤)。女性19例,男性1例。平均年龄40岁,持续症状1.4年。表现的体征、症状,以颅神经功能障碍和头痛最常见。对患者平均随访1年。多数患者在一期(48%)或二期(39%)切除病变。最常见的手术并发症是面神经麻痹,其次是血管错位、外展神经受累及脑脊液(CSF)漏。20例患者中有18例完全切除病变,术后反应良好,2例表皮样瘤几乎全切除病变。
Skull base tumors invade slopes, petrosal bones, and adjacent areas. It is difficult to successfully remove tumors without damaging important nerves. In the last 5 years, 103 patients with tumors of the skull base have been treated, and 20 of them have been reviewed by supraconjugative approach to remove tumors (9 cases of schwannoma, 6 cases of meningioma, 2 cases of epidermoid tumor, 1 case of extensive Basal cell carcinoma, 1 case of spondyloarma and 1 case of basilar aneurysm). There were 19 females and 1 male. The average age is 40 years and the symptoms last for 1.4 years. Signs and symptoms of manifestation are most common with cranial nerve dysfunction and headache. The patients were followed up for an average of 1 year. Most patients had their lesions removed in one stage (48%) or two stages (39%). The most common surgical complication was facial nerve palsy, followed by vascular dislocation, abducens nerve involvement, and cerebrospinal fluid (CSF) leakage. Eighteen of the 20 patients had complete resection of the lesions, and the postoperative response was good. Two cases of epidermoid neoplasia were completely resected.