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为了解原发性肝癌肿瘤浸润淋巴细胞（ＴＩＬ细胞）治疗肝癌的临床价值及应用前景，采用Ｒｏｓｅｎｂｅｒｇ法，对ＴＩＬ细胞的分离、培养及抗瘤活性进行了研究。结果８例肝癌病人的ＴＩＬ细胞分离、培养均获得成功，并在培养３～５周后扩增到临床治疗肝癌所需的ＴＩＬ细胞数量。抗瘤活性测定表明ＴＩＬ细胞对肝癌细胞有一定的杀伤力。显示了ＴＩＬ细胞治疗肝癌有一定的临床价值和应用前景。
To understand the clinical value and application prospects of primary hepatocellular carcinoma infiltrating lymphocytes (TIL cells) in the treatment of liver cancer, Rosenberg method was used to study the isolation, culture and antitumor activity of TIL cells. Results The isolation and culture of TIL cells in 8 cases of liver cancer patients were successful. After 3 to 5 weeks of culture, the number of TIL cells required for clinical treatment of liver cancer was amplified. The anti-tumor activity assay showed that TIL cells had a certain lethal effect on hepatoma cells. Shows that TIL cells have a certain clinical value and application prospects in the treatment of liver cancer.