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【目的】评价复感宁方(五爪龙、太子参、茯苓、薏苡仁、人参叶、芒果核、鸡内金、甘草)治疗肺脾气虚夹湿夹滞型小儿反复呼吸道感染(RRTI)的临床疗效和兼症的改善情况,并进一步探讨复感宁方的立法依据和作用机理。【方法】随机将60例肺脾气虚夹湿夹滞型复感患儿分为治疗组和对照组,每组各30例。治疗组于缓解期给予中药复感宁方治疗,对照组给予胸腺肽片口服治疗,两组均以8周为1个疗程,随访3个月,比较两组总疗效和治疗前后兼症改善情况。【结果】治疗组30例,显效7例,有效20例,无效3例,总有效率为90.00%;对照组30例,显效2例,有效21例,无效7例,总有效率为76.67%;两组比较,治疗组疗效优于对照组(P<0.05)。治疗组治疗后,食欲不振、多汗、大便不调、面色少华等兼症的改善亦优于对照组(P<0.05)。【结论】复感宁方对肺脾气虚兼夹湿夹滞型RRTI有确切的临床疗效,并能明显改善食欲不振、大便不调、多汗、面色少华等症状,在达到防治目的的同时提高了患儿的生活质量,起到整体调治的作用。
【Objective】 To evaluate the effects of Fuganningfang (Wutiao, heterophylla, Poria cocos, Coix seed, ginseng leaf, mango nucleus, chickweed gold and licorice) in the treatment of children with recurrent respiratory tract infections (RRTI) Clinical efficacy and the improvement of concurrent symptoms, and to further explore the legislative basis and mechanism of Fuganning Fang. 【Methods】 Sixty children with pulmonary spleen qi and wet folder syndrome were randomly divided into treatment group and control group, with 30 cases in each group. The treatment group was treated with Fufang Ning Fang in the remission period while the control group was treated with thymosin tablets orally. Both groups were given a course of treatment for 8 weeks and were followed up for 3 months. The total curative effect and the improvement of the disease before and after treatment were compared between the two groups. 【Results】 The treatment group, 30 cases, markedly effective in 7 cases, effective in 20 cases, invalid in 3 cases, the total effective rate was 90.00%; control group of 30 cases, markedly effective in 2 cases, effective in 21 cases, ineffective in 7 cases, the total effective rate was 76.67% The curative effect of treatment group was better than that of control group (P <0.05). Treatment group, the loss of appetite, hyperhidrosis, stool is not adjusted, looking shabby and other symptoms of improvement is also better than the control group (P <0.05). 【Conclusion】 Fufangningfang has definite clinical curative effect on RRTI of lung, spleen and asthenia, and can obviously improve the symptoms of poor appetite, loose stool, hyperhidrosis, Improve the quality of life of children, played the role of the overall regulation.